Topics

Tumor Nomenclature

Tumor Grade Vs. Stage Grade  histologic assessment of how closely a neoplasm resembles the original tissue

Cholangiocarcinoma

Snapshot A 35-year-old man with a history of primary sclerosing cholangitis presents with two

Oncogenic Viruses

Overview Virus Associated Cancer EBV  CNS lymphoma (AIDS)Burkitt’s lymphomaNasopharyngeal carcinoma  HBV, HCV  Hepatocellular carcinoma

Pancreatic Cancer

Snapshot A 69-year-old man presents to the emergency department with generalized fatigue and abdominal

Parathyroid Adenoma

Snapshot A 45-year-old woman presents with pain and achiness in her joints and bones,

Angiosarcoma

Snapshot A 75-year-old man presents to the clinic with complaints of generalized fatigue and

Endometrial Carcinoma

Snapshot A 58-year-old woman presents to her gynecologist for vaginal bleeding. She denies any

Alkylating Agents

Overview Drugs Mechanism of Action Toxicity Cyclophosphamide and ifosfamide Crosslinks DNA Hemorrhagic cytitis and

Antitumor Antibiotics

Dactinomycin (Actinomycin D) Mechanism  intercalate between strands of DNA Clinical use Wilms’ tumor Ewing’s sarcoma