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Biochemistry

Population Genetics

Overview Forces responsible for genetic variation mutation de novo mutation rates constant among populations

Collagen

Synthesis and Structure Inside fibroblasts  pre-pro-collagen α chain formation RER-bound ribosomes synthesize contains hydrophobic

RNA Processing

Overview Only in eukaryotes pre-processed transcript = hnRNA Process  capping 5′ end 7-methylguanosine cap

Protein Synthesis

RibosomeStructure eukaryotes small subunit (40S) synthesized in the nucleus large subunit (60S) synthesized in

Glycolysis

Overview Glycolysis is a metabolic pathway that occurs in the cytoplasm of cells and

Gluconeogenesis

Overview  Function de novo glucose synthesis effectively glycolysis in reverse can maintain blood glucose

Glycogen

Overview  Structure glycogen polymer of glucose straight chain with α-1,4-bond branches with α-1,6-bond glycogen

Microtubules

Overview Introduction  cellular structural protein with a hollow tubular structure Structure composed of polymerized dimers

Genetic Principles

Principles Codominance both allelic copies are expressed e.g.) blood groups (A, B, AB) Variable

DNA Repair

Damage Tolerance Function can allow DNA replication to continue despite presence of DNA damage (e.g.

Fat Soluble Vitamins

Overview Examples  A D E K Characteristics precursors for coenzymes pancreatic enzymes required for absorption in

Amino Acid Catabolism

Overview Three possible fates enter citric acid cycle form ketone bodies substrates for gluconeogenesis