Endocrine

Somatropin Growth hormone (GH) mimetic Mechanism agonist at GH receptors increases production of insulin growth

Introduction Apparent alterations to thyroid hormone level with normal thyroid gland function peripheral activity of outer

Presentation Symptoms depend on specific hormone deficiency ↓ FSH/LH impotence (males), amenorrhea (females) late-onset

Snapshot A 3-year-old girl is brought to the emergency room after her parents felt

Introduction May be hot or cold  hot signifies thyroid hormone production with 131I uptake cold signifies no

Introduction Diabetic symptoms as result of genetic mutations in metabolic transcription factor genes many different loci

Overview Gross anatomy  islets of Langerhans most numerous in tail of pancreas  exocrine pancreas more

Overview: Hypothalamic-Pituitary Axis Regulatory Mechanisms  Hypothalamus-Released Hormone Regulatory Mechanism  Anterior Pituitary-Released Hormone GnRH Stimulates

Introduction Calcium homeostasis controlled by a combination of  vitamin D and PTH  PTH Pathway

Overview Properties  solubility lipophilic insoluble in plasma transportation must circulate bound to globulin proteins

Overview General mechanism releasing hormone (IP3) → pituitary hormone (cAMP) → systemic hormone (steroid)

Overview Synthesis  made in parafollicular cells (C cells) of thyroid in response to hypercalcemia inferior