Immunology

Snapshot A 12-year-old boy presents to the emergency department with dyspnea and urticaria. His

Snapshot A 7-year-old presents to the pediatrician with a “white tongue.” On physical exam,

Snapshot Recombinant Cytokines Introduction Immunosuppressants Medication Mechanism of Action Clinical Use Aldesleukin IL-2 product

Snapshot – Superantigens Introduction Overview Superantigens are potent immune system activators that can trigger

Introduction Importantly, allogenic MHC (from another individual) can be recognized as foreign by the

Introduction Major Histocompatibility Complex (MHC) deficiency refers to a group of rare genetic disorders

Overview Introduction (Antibody-Dependent Cell-Mediated Cytotoxicity) Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) is a vital immune mechanism

Snapshot (Ataxia-Telangiectasia) Introduction Ataxia-Telangiectasia (A-T) is a rare, autosomal recessive genetic disorder that affects

Snapshot Introduction Selective IgA deficiency is a relatively common primary immunodeficiency characterized by low

Snapshot (Common Variable Immunodeficiency Disorder) Common Variable Immunodeficiency Syndrome Pathophysiology Abnormal differentiation of B

Introduction Antigen processing and presentation is a fundamental immune mechanism that allows the immune

Introduction  Primary lymphoid tissue is a critical component of the immune system, where immune