Immunology

Snapshot A 12-year-old boy presents to the emergency department with dyspnea and urticaria. His

Snapshot A 7-year-old presents to the pediatrician with a “white tongue.” On physical exam,

Snapshot Recombinant Cytokines Introduction Immunosuppressants Medication Mechanism of Action Clinical Use Aldesleukin IL-2 product

Snapshot – Superantigens Introduction Overview Superantigens are potent immune system activators that can trigger

Introduction MHC Classes  Differences Between MHC Classes Feature MHC Class I  MHC Class II 

Introduction Major Histocompatibility Complex (MHC) deficiency refers to a group of rare genetic disorders

Overview Introduction (Antibody-Dependent Cell-Mediated Cytotoxicity) Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) is a vital immune mechanism

Snapshot (Ataxia-Telangiectasia) Introduction Ataxia-Telangiectasia (A-T) is a rare, autosomal recessive genetic disorder that affects

Snapshot Introduction Selective IgA deficiency is a relatively common primary immunodeficiency characterized by low

Snapshot (Common Variable Immunodeficiency Disorder) Common Variable Immunodeficiency Syndrome Pathophysiology Abnormal differentiation of B

Introduction Antigen processing and presentation is a fundamental immune mechanism that allows the immune

Introduction  Primary lymphoid tissue is a critical component of the immune system, where immune