Oncology

Prostate Cancer

Snapshot A 68-year-old man presents to his primary care physician for an annual examination.

Myelofibrosis

Introduction Neoplasia of mature myeloid cells most notably megakaryocytes Most commonly seen in older adults

Metastasis

Introduction Spread of a neoplasm to distant tissues Cellular requirements invasive carcinoma progression that

Testicular Tumors

Introduction Testicular tumors can be of germ cell or non-germ cell origin germ cell

Tumor Markers

Overview Proteins released by neoplasm into circulation Tumor markers should be used to confirm

Gastric Cancer

Snapshot A 56-year-old man presents to his primary care physician for abdominal pain. His

Principles of Neoplasia

Overview Acquired abilities of neoplastic tissue  apoptotic evasion self-sustained monoclonal growth all cells in

Microtubule Inhibitors

Vinca Alkaloids (Vincristine and Vinblastine) Mechanism  block microtubule formation  bind to tubulin in M

Targeted Therapy

Overview Drugs/Antibodies Mechanism of Action Toxicity Hydroxyurea Inhibits ribonucleotide reductase GI upset and myelosupression

Benign Bone Tumors

Snapshot A 12-year-old boy develops mild pain in his right leg. The pain is

Polycythemia Vera

Snapshot A 59-year-old woman presents to her primary care physician with overwhelming fatigue, headaches,