Pathology

Leukocyte Extravasation

Overview Introduction Leukocytes play an important role in eliminating offending agents neutrophils and macrophages

Infarcts

Overview Decreased tissue oxygen results in reduced ATP production and cell death Can occur

Free Radical Injury

Overview Free radicals are chemical compounds with unpaired electrons in the valence shell a cascade is initiated

Transudate vs. Exudate

Overview   Transudate  Exudate  Cellularity Hypocellular Cellular Protein Poor Rich Specific gravity < 1.012

Cell Injury

Overview Introduction Cells constantly interact with their environment and try to maintain homeostasis cells

Amyloidosis

Overview Amyloid is misfolded protein that takes the form of a beta-pleated sheet the protein

Necrosis

Overview Exogenous cell injury resulting in uncontrolled cell degradation  normal cellular enzymes responsible for

Psammoma Bodies

Overview Onion-skinned and calcified histology represent malignant calcification  Associated with papillary adenocarcinoma of thyroid 

Shock

Overview Different Types of Shock Shock Type Skin  Wedge Pressure (PCWP) (Preload) Systemic Vascular

Apoptosis

Overview Programmed cell death  requirements ATP functioning caspase enzymes for cellular degradation  break down cytoskeleton degrade