Hematology

Vitamin K Deficiency

Introduction Disruption of all vitamin K-dependent factors II, VII, IX, X, protein C, protein

Sideroblastic Anemia

Snapshot A 35-year-old man presents to the clinic for follow-up for treatment of latent

Thrombogenesis

Overview Always a balance between pro-aggregation and anti-aggregation forces Formation of a platelet plug occurs in

Thrombolytics

Overview Thrombolytics catalyze the formation of endogenous plasmin from plasminogen precursor plasmin is a serine protease that degrades

Microangiopathic Anemia

Introduction RBCs are damaged in systemic circulation due to sharp microthrombi lining small vessels Associated conditions

Anemia of Renal Failure

Snapshot A 45-year-old man with history of stage 5 chronic kidney disease presents with

Factor V Leiden

Snapshot A 25-year-old Caucasian woman presents with her right calf larger than her left.

Coagulation Factor Inhibitor

Introduction Autoantibody against a coagulation factor Anti-Factor VIII is the most common recall factor VIII

Transfusion

Overview Common/minor adverse reactions to blood transfusion febrile non-hemolytic transfusion reaction occurs a few

Pyruvate Kinase Deficiency

Snapshot A newborn baby with a history of hyperbilirubinemia at birth requiring phototherapy is

Folic Acid Deficiency

Snapshot A 25-year-old woman presents to her obstetrician at 22-weeks pregnant. She had no