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Microangiopathic Anemia

Introduction

image 2022 09 12T124546.052
image 174

  • RBCs are damaged in systemic circulation due to sharp microthrombi lining small vessels
  • Associated conditions
    • DIC
    • TTP-HUS
    • SLE
  • malignant hypertension

Presentation

  • Symptoms
  • anemia

Evaluation

  • Blood smear 
    • schistocytes (helmet cells) (indicated by arrow in image above)
      • due to shearing mechanical destruction