Oncology

Vaginal Carcinoma

Snapshot A 62-year-old woman reports having abnormal vaginal bleeding that occurs intermittently between her predictable menstrual cycles.

Hodgkin Lymphoma

Snapshot A 15-year-old boy presents with fatigue and masses around his neck. The masses

Oncogenes

Overview Mechanism  gain of function mutation in a proto-oncogene due to novel protein function

Platinum Analogs

Cisplatin and Carboplatin Mechanism crosslinks DNA platinum atom binds to DNA bases Clinical use

Tumor Nomenclature

Tumor Grade Vs. Stage Grade  histologic assessment of how closely a neoplasm resembles the original tissue

Cholangiocarcinoma

Snapshot A 35-year-old man with a history of primary sclerosing cholangitis presents with two

Oncogenic Viruses

Overview Virus Associated Cancer EBV  CNS lymphoma (AIDS)Burkitt’s lymphomaNasopharyngeal carcinoma  HBV, HCV  Hepatocellular carcinoma

Pancreatic Cancer

Snapshot A 69-year-old man presents to the emergency department with generalized fatigue and abdominal

Parathyroid Adenoma

Snapshot A 45-year-old woman presents with pain and achiness in her joints and bones,