Overview P450 Inducers P450 Inhibitors St. John’s WortPhenytoinBarbituratesRifampinGriseofulvinCarbamazepine EfavirenzModafinilCyclophosphamideBroccoli, brussel sprouts, and char-grilled meatsEthanol Tricyclic
Overview Ganglionic Blockers Ganglionic blockers, also known as ganglionic blocking agents, are a class
Overview – Central and Peripheral Nervous System ACh receptors What Is the Central and
Overview What is Phase I Metabolism? Phase I metabolism refers to the initial metabolic
Competitive vs. noncompetitive antagonist (Pharmacodynamics) Agonist vs. partial agonist Synergism & Potentiation Overview Pharmacodynamics
Overview (Efficacy vs. Potency) Efficacy vs. Potency Efficacy and potency are two important concepts
Snapshot Introduction (Salicylate/Aspirin Overdose) Presentation Studies Differential Treatment Treatment for salicylate overdose typically involves
Overview Therapeutic Index The therapeutic index (TI), also known as the therapeutic window, is
Introduction – Autonomic Pathways The autonomic nervous system (ANS) is the part of the
Alpha-Blockers Drug Clinical Applications Toxicity Nonselective α-Blockers Phenoxybenzamine (irreversible, preferred) • Pheochromocytoma • High catecholamine states
Overview – Drug Excretion Weak acids and bases Drug Excretion Drug excretion refers to
