Psychiatric Drug Introduction
- Psychiatric medications can be broken down into the following categories
- Antidepressants
- Antipsychotics
- Bipolar Medications
- Anxiolytics
Overview
- Buproprion
- mechanism
- ↑ NE and dopamine via unknown mechanism
- other uses
- smoking cessation
- toxicity
- stimulant effects (tachycardia, insomnia)
- headache
- seizure in bulimic patients
- no sexual side effects
- mechanism
- Mirtazapine
- mechanism
- α2 receptor antagonist
- ↑ release of NE and serotonin
- 5-HT2 and 5-HT3 receptor antagonist
- α2 receptor antagonist
- other uses
- depression + anorexia nervosa
- due to weight gain side effect
- depression + anorexia nervosa
- toxicity
- sedation, ↑ appetite, weight gain, dry mouth
- mechanism
- Amoxapine
- mechanism
- antagonism of dopamine receptor
- toxicity
- EPS, seizures, cardiotoxicity
- mechanism
- Maprotiline
- mechanism
- blocks NE reuptake
- toxicity
- sedation, orthostatic hypotension, seizures, cardiotoxicity
- mechanism
- Trazodone
- mechanism
- primarily inhibits serotonin reuptake
- other uses
- causes sedation
- therefore used for insomnia
- high doses are needed for antidepressant effects
- causes sedation
- toxicity
- sedation, nausea, priapism in adolescent boys, orthostatic hypotension
- mechanism