Snapshot
Introduction
- Insufficient iodine intake or defect in T4/thyroid formation leading to fetal hypothyroidism
- T4 is crucial during first two years of life for normal brain development
- Cretinism refers to
- untreated congenital hypothyroidism
- leads to congenital defects and physical abnormalities
Presentation
- Symptoms
- severe mental retardation
- increased weight and short stature
- coarse facial features
- large protuding tounge
- umbilical hernia
Evaluation
Treatment
Treat with levothyroxine replacement
Prognosis, Prevention, and Complications
Prevention by newborn screening by law