Expectorants

Overview

Guaifenesin (Robitussin)
- removes excess sputum
- does not suppress cough reflex
- must use large doses
N-acetylcysteine
- mucolytic
  - cleaves disulfide bridges between mucus glycoproteins
  - loosens mucus plugs in CF patients
- also used as an antidote for acetaminophen overdose
Dextromethorphan
- over the counter cough suppressant
- side effect of constipation
- overdose can lead to hallucinations

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Expectorants

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