| Symptoms/Physical Exam |
| Hypothyroidism | Hyperthyroidism |
| Cold intolerance (↓ heat production) | Heat intolerance (↑ heat production) |
| Weight gain↓ appetite | Weight loss↑ appetite |
| HypoactivitylLethargyFatigueWeakness | Hyperactivity |
| Constipation | Diarrhea |
| ↓ reflexes | ↑ reflexes |
| Bradycardia | Tachycardia, palpitations, arrhythmias |
| Dry, cool skinCoarse, brittle hair | Warm, moist skinFine hair |
Diastolic hypertension (Na/H
2O retention) | Systolic hypertension |
| Myxedema (facial/periorbital) | Osteoporosis |
