Methylphenidate (Ritalin)

Introduction

Mechanism of action
- inhibits the reuptake of norepinephrine (NE) and dopamine (DA) into presynaptic neurons
  - this increases the amount of NE and DA in the synaptic cleft thus stimulating postsynaptic neurons with NE and DA receptors
Clinical use
- Attention Deficit Hyperactivity Disorder (ADHD)
- Narcolepsy

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Methylphenidate (Ritalin)

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