Snapshot
- A 60-year-old man with a history of benign prostatic hyperplasia presents to his primary care physician for a 3-day period of fever, chills, and pain with urination. He was recently catheterized during an admission in the hospital. Physical exam reveals a tender and enlarged prostate on digital rectal exam. Urinalysis reveals pyuria and hematuria. He is started on empiric antibiotics.
Introduction
- Clinical definition
- infectious or non-infectious inflammation of prostate
- acute prostatitis
- typically infectious
- chronic prostatitis
- can be due to recurrent infections lasting > 3 months (10% of chronic prostatitis)
- can be due to chronic pelvic pain (90% of chronic prostatitis)
- > 3 months of pain in the absence of other identifiable causes
- noninfectious etiology but often unknown
- can be due to trauma, psychological stress, and increased prostate tissue pressure
- Epidemiology
- incidence
- 10-15% men have it once in their lifetime
- risk factors
- catheterization
- incidence
- benign prostatic hypertrophy
Presentation
- Symptoms
- dysuria
- urinary frequency
- urinary urgency
- straining with urination or interrupted stream (obstruction)
- lower back pain
- Physical exam
- fever
- chills
- digital rectal exam
- enlarged prostate
- very tender on exam may indicate acute prostatitis
- less tender on exam may indicate chronic prostatitis
Studies
- Urine studies for bacterial infection
- urinalysis
- pyuria
- hematuria
- urinalysis
- urine culture
Differential
- Urinary tract infection
- Urethritis
Treatment
- Medical
- antibiotics
- indications
- acute or chronic bacterial infection
- drugs chosen empirically based on local resistance patterns
- uropathogens
- trimethoprim and sulfamethoxazole
- fluoroquinolone
- sexually transmitted pathogens
- ceftriaxone
- azithromycin
- uropathogens
- indications
- α-blockers
- indications
- chronic pelvic pain syndrome or noninfectious chronic pain
- typically given alongside a fluoroquinolone for initial therapy
- drugs
- indications
- antibiotics
- tamsulosin
Complications
- Prostatic abscess