| Select Central Nervous System Lesions |
| Lesion | Clinical Features |
| Frontal lobe | Frontal lobe lesions can result in disinhibition and an impairment injudgmentorientationconcentrationfrontal release signsmagnetic gaitFrontal eye field (FEF) lesions can result ineye deviation towards the side of the lesionan example is a stroke affecting the FEF |
| Parietal lobe | Lesions affecting thedominant parietal (usually the left) cortex results in Gerstmann’s syndromeagraphiaacalculiafinger agnosiaright-left confusionnon-dominant (usually the right) parietal cortex results incontralateral hemineglectdistortion of perceived spaceextinction |
| Temporal lobe | Lesions affecting the superior temporal lobe (Wernicke area) can result Wernicke aphasia and a right superior quadrant visual defect Lesions affecting limbic structures can result in deficits inconsolidation and behavioral changesSeizures in the medial temporal lobe limbic structures results inemotions such asfeardeja vuolfactory hallucinationsBilacteral lesions in the amygdala results inKluver-Bucy syndrome |
| Brainstem | Lesions affecting thesuperior colliculusParinaud syndromereticular activating systemdecreased consciousness and comabasal gangliaresting tremorchoreaathetosismedial longitudinal fasciculusinternuclear ophthalmoplegiaparamedian pontine reticular formationeyes look aways from the side of the lesion |
