Signaling Pathways of Endocrine Hormones

Overview

General mechanism
- releasing hormone (IP₃) → pituitary hormone (cAMP) → systemic hormone (steroid)
  - GnRH → FSH/LH → estrogen/testosterone/progesterone
  - TRH → TSH →T₃/T₄
- vasoactive hormones
  - cGMP
- growth factors
  - tyrosine kinase
    - MAP kinase
- growth hormone, cytokines, hormones
  - receptor tyrosine kinase
    - JAK/STAT

IP₃	cAMP	cGMP	Tyrosine Kinase (MAP Kinase)	Non Receptor Tyrosine Kinase – (JAK/STAT)	Steroid
GnRH	FSH	ANP	Insulin	Prolactin	Glucocorticoid
Gastrin	LH	NO (EDRF)	IGF-1	Immunomodulators (IL-2,6, and IFN)	Estrogen
Oxytocin	ACTH		FGF	GH	Progesterone
TRH	TSH		PDGF	G-CSF	Testosterone
ADH (V₁)	CRH		EGF	Erythropoietin	Aldosterone
Histamine (H₁)	hCG			Thrombopoietin	Vitamin D
Angiotensin II	PTH				T₃/T₄
	Calcitonin				Cortisol
	Glucagon
	GHRH (can act via IP3as well)

We at USMLEStrike® precisely adopt the unique strategies in our educational process to ensure that every student here enjoys learning the syllable knowledge along with acquiring wisdom for life.

Useful Links

Information

Socials

Copyright © 2024 USMLEStrike®. All rights reserved.

© Designed and Developed By Cloudstar Digital