Urinary Incontinence

Snapshot

  • A 42-year-old woman presents to her primary care physician due to involuntary passage of urine. She reports to voiding small amounts of urine throughout the day and night. She says that this occurs without warning. Medical history is significant for multiple sclerosis treated with ocrelizumab. Physical examination is notable for a distended bladder. (Overflow incontinence secondary to multiple sclerosis)

Introduction

  • Clinical definition
    • involuntary urinary leakage
  • Diagnostic studies
    • all patients with urinary incontinence should have a urinalysis
    • if symptoms are concerning for a urinary tract infection obtain a urine culture
Urinary Incontinence
TypePathogenesisPresentationDiagnosisTreatment
Stress incontinenceMay be secondary to a number of factors such asweakened pelvic floor musclese.g., vaginal deliveriespoor intrinsic sphincter functionincreased urethral mobility Urinary incontinence with ↑ intra-abdominal pressuree.g., coughing, sneezing, laughing, and physical exertionNo urine loss at nightPhysical exama cystocele may be present Q-tip testStrengthening the pelvic floor muscles via Kegel exercisesfirst-lineTopical estrogen for post-menopausal womenPessaryMidurethral sling in patients unresponsive to initial therapy and pessary
Urge incontinenceDetrusor muscle overstimulation  Frequent urinary leakage that also occurs at nightdisrupts sleepUrge to urinate and may be unable to reach the bathroom in timeUrodynamic testingAntimuscarinics e.g., oxybutyninMirabegron
Overflow incontinenceIncomplete bladder emptying results in urinary leakage secondary todetrusor muscle underactivity e.g., age, diabetes mellitus, and multiple sclerosisbladder outlet obstructione.g., fibroids and benign prostatic hyperplasiaUrine loss without warning or triggersPost-void residual volume measurementsUrodynamic testingClean intermittent catheterization
Mixed IncontinenceSymptoms of both stress and urge incontinenceLifestyle modifications and pelvic floor exercises are first-lineIf unresponsive to first-line treatments then therapy is based on the predominant symptoms