Waterhouse-Friderichsen Syndrome

Introduction

Cause of acute adrenocortical insufficiency
Typically follows Neisseria meningitidis septicemia
- infection causes endotoxic shock and DIC
leads to consequent bilateral adrenal hemorrhage and infarction

Presentation

Physical exam
- meningitis with petechial lesions

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Waterhouse-Friderichsen Syndrome

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